| NSX-V | NSX-T | |
| Tight integration with vSphere | Yes | No |
| Works without vCenter | No | Yes |
| Support for multiple vCenter instances | No | Yes |
| Supported virtualization platforms | VMware vSphere | VMware vSphere, KVM, Docker, Kubernetes, OpenStack, AWS native workloads |
| NSX Edge deployment | ESXi VM | VM or physical server |
| Overlay encapsulation protocols | VXLAN | GENEVE |
| Virtual switches (N-VDS) | vSphere Distributed Switch (VDS) | Open vSwitch or VDS |
| Logical switch replication modes | Unicast, Multicast, Hybrid | Unicast (Two-tier or Head) |
| ARP suppression | Yes | Yes |
| A two-tier distributed routing | No | Yes |
| Configuring the IP addressing scheme for network segments | Manual | Automatic (between Tier 0 and Tier 1) |
| Integration for traffic inspection | Yes | No |
| Kernel-level distributed firewall | Yes | Yes |